Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Calcium Channel - Imagabalin hydrochloride

Imagabalin hydrochloride

CAS No. 610300-00-0

Imagabalin hydrochloride( PD-0332334 | PD-332334 )

Catalog No. M15290 CAS No. 610300-00-0

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Imagabalin hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.
  • Description
    Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2; demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.Anxiety Phase 3 Discontinued.
  • In Vitro
    ——
  • In Vivo
    β-Amino Acid Imagabalin Hydrochloride had been in phase III clinical trials for the treatment of generalised anxiety disorders. However, this research has been discontinued. β-Amino Acid Imagabalin Hydrochloride had been also in phase I clinical trials for the treatment of chronic kidney disease.
  • Synonyms
    PD-0332334 | PD-332334
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    610300-00-0
  • Formula Weight
    209.714
  • Molecular Formula
    C9H20ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCC[C@@H](C)C[C@H](N)CC(O)=O.[H]Cl
  • Chemical Name
    (3S,5R)-3-amino-5-methyloctanoic acid hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Quintero JE, et al. Brain Res. 2011 Jul 15;1401:1-9.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TTA-Q6

    TTA-Q6, a selective T-type Ca2+ channel antagonist, exhibits potential antitumor and immunomodulatory activities for treating neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells, thereby inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress.

  • Nicardipine

    Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension.

  • Atagabalin

    Atagabalin (PD 0200390) is a novel ligand of the voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) for treatment for insomnia.

Sign In Join Free